The most important game of the weekend might actually occur in Las Vegas in a game that could have massive ramifications for the 2026 draft.

The Buffalo Bills (11-4) will go up against the Philadelphia Eagles (10-5) at Highmark Stadium on Sunday. Buffalo opens as 1.5-point favorites from Vegas oddsmakers. The betting total comes in at 43.5.

In Week 1, the Seahawks lost 17-13 to the 49ers, and in that game, both Darnold and Jaxon Smith-Njigba fumbled the ball away in the fourth quarter. In Week 5, the Seahawks lost 38-35 because their defense couldn't stop Baker Mayfield, who threw for 379 yards. In Week 11, the Seahawks lost to the Rams because Darnold threw four interceptions.