Background: In this article, we discuss the purpose of sample size calculation in clinical trials, the need for it, and the methods by which it is accomplished. Study samples that are either too small ...

Biometrics is a scientific journal emphasizing the role of statistics and mathematics in the biological sciences. Its object is to promote and extend the use of mathematical and statistical methods in ...

Investigator: Right, here is the data set. What is the P value? Statistician: Oh, hello again. Look, I have some concerns about how the endpoint was assessed... Investigator: Fine, I'll add a sentence ...

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...