Recent advances in the techniques that are used to design and prepare protein domains have led to the realization that several proteins, which are involved in important cellular processes, contain ...

Heat shock proteins of 40 kDa (Hsp40s), also called J proteins, are obligate partners of Hsp70s. Via their highly conserved and functionally critical J domain, J proteins interact and modulate the ...

Heat shock 70 kDa proteins (HSP70s) are ubiquitous molecular chaperone machines, with the core consisting of an HSP70, a J protein and a nucleotide exchange factor (NEF). These machines function in a ...