The human immune system is split into the innate immune system and the adaptive immune system. Both systems work in harmony to protect us from infections and disease. Here, we discuss their ...

This is part of a series of stories on the protective role of innate lymphoid cells (ILCs) in the gut and other tissues, focusing on SARS-CoV-2 infection. One area that hasn’t received all that much ...

At one time, natural killer cells were thought of as a small group of specialized immune cells that can rapidly identify and destroy cells that have been infected with a virus. But research has shown ...

The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

The current coronavirus disease 2019 (COVID-19) pandemic has posed a major public health crisis and has affected all nations across the globe. The disease is caused by the spread of the severe acute ...

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection ...

When the worldwide death toll from Covid-19 surpassed five million two weeks ago, it served as a grim reminder that more than lockdowns and vaccines will be needed to end the pandemic. A new study, ...

"Training" of precursors of white blood cells leads to a sustained positive response of the hematopoietic system. This effect could help accelerate the formation of new white blood cells, which are ...

Researchers from Penn’s School of Dental Medicine discovered that training the innate immune system may lead to increased bone loss in inflammatory conditions such as periodontitis and arthritis.