Watch the top defensive plays from Week 16 of the 2025 NFL season. Highlights from the Week 16 matchup between the San Francisco 49ers and the Indianapolis Colts during the 2025 NFL season.

The last of the ABC22/FOX44 Top Plays of the Year semifinal nominees are here VOTE HERE Ken Drake will have the results coming up on Friday 12/26

DK Metcalf $5400: The Steelers are playing for the playoffs. Metcalf is 6’4” and 229 pounds. The Lions' depleted secondary averages 5’9” and around 190 pounds. Metcalf should dominate this mismatch.

Watch the best plays by the San Francisco 49ers against the Indianapolis Colts in Week 16 of the 2025 NFL season.

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Watch the New Orleans Saints' top play highlights vs. the Carolina Panthers in Week 15 of the 2025 NFL season.

Check out the NFL Week 16 most bet anytime touchdown scorers at BetMGM, highlighting where bettors are backing proven red-zone roles and scoring opportunities.

NFL Week 17 is here and we’ve got the best NFL bets you need to know! Geoff Schwartz, and Sammy Panayotovich break down their best NFL bets to place right now. If you’re looking for NFL Week 17 best bets,

RotoBaller's Week 15 NFL DFS value plays, sleeper picks, and tournament stacks for daily fantasy football on FanDuel, DraftKings, and Yahoo. Win big in DFS with our expert research and advice.