Heading into Week 6 of the 2025 NFL season, we continue to track the winning ways of road favorites. After going 3-2 against the spread last week, road favorites are now 16-10 on the season — a winning percentage of .

The league's latest round of games begins with a heated NFC East rivalry and ends with yet another Monday night doubleheader.

Sam Farmer makes his picks and predictions for Week 6 of the NFL season, with the Lions defeating the Chiefs in prime time and the Seahawks improving to 4-2.

Also, let's not ignore the tremendous season that Sam Darnold is putting together for the Seahawks. Remarkably, his completion percentage and passer rating are even better than what he produced last season with the Vikings. I think he leads Seattle into Duval County and leaves with an outright win.

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