One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of Pharmaceutical Sciences, Toho University, has demonstrated that overexpression of Cdc10 ...
New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.
Discover how a tiny RNA molecule serves as a molecular switch in viral infections, providing insights into phage biology.
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Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...
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The Shape of Your DNA Matters

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...
Using drugs that inhibit enzymes called CDK4/6 and CDK2 extends the G1 phase of the cell cycle and helps to slow the growth of drug-resistant breast cancer.
Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to ...
One ocean-dwelling creature found in many tropic waters is known to be able to reserve its own life cycle, cheating death.