In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...
New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
Scientists engineered stem cells with “interrupted” CAG repeats to break up the toxic stretch. This may stop expansion, and could improve problems in cells that model Huntington’s disease. This study ...
New method ASPEN accurately maps gene activity from each parent in individual cells, overcoming noise in data. It revealed ...